《Approaches To Tumor Chemotherapy》

General Review of Cancer Therapy＆WILLIAM H．WOGLOM1

The Transparent Chamber Technique as a Tool in Experimental Tumor Therapy＆GLENN H．ALGIRE13

Some Cellular and Surface Chemical Aspects of Tumor Chemotherapy＆M．J．KOPAC27

A Method of Producing Oncolysis in Rats That Conferred a Certain Immunity Against Homologous Tumors＆PAUL APTEKMAN58

The Chemistry of Substances Specific for the Stimulation of Lymphopoiesis and Myelopoiesis＆D．L．TURNER AND F．R．MILLER64

A Myeloid Metaplasia Factor from Human Urine＆R．W．HEINLE，H．HIRSCHMANN，AND J．T．WEARN77

The Role of Nutrition in the Origin and Growth of Tumors＆ALBERT TANNENBAUM96

The Influence of Diet on the Production of Hepatic Tumors Induced by p-Dimethylaminoazobenzene＆EUGENE L．OPIE128

Chemotherapeutic Regressions of Transplanted and Spontaneous Cancers in Mice139

Ⅰ．Review of the Work of the Laboratory，1937-1945＆RICHAED LEWISOHN139

Ⅱ．Studies on Tumor Growth-Inhibitory Substances＆DANIEL LASZLO148

Ⅲ．Results of Treatment of Spontaneous Tumors with ＂Folic Acid＂ and Allied Substances＆CECILIE LEUCHTENBERGER157

Ⅳ．Histological Changes Occurring in Breast Cancers of Mice Treated with Folic Acid＆RUDOLF LEUCHTENBERGER163

Effect of Intravenous Injection of Yeast and Barley Extracts and L．Casei Factor upon Spontaneous Mammary Adenocarcinoma in Mice＆KANEMATSU SUGIURA208

Note：The Growth-Inhibition of Mouse Sarcoma 180＆PAUL A．ZAHL AND S．H．HUTNER214

A Review of the Treatment of Malignant Tumors by Coley Bacterial Toxins＆HELEN COLEY NAUTS AND BRADLEY L．COLEY217

Some Aspects of a Joint Institutional Research Program on Chemotherapy of Cancer：Current Laboratory and Clinical Experiments with Bacterial Polysaccharide and with Synthetic Organic Compounds236

Ⅰ．Scope of the Program＆M．J．SHEAR236

Ⅱ．Organic Chemistry＆JONATHAN L．HARTWELL241

Ⅲ．Method Used in Screening Compounds for Potency＆VIRGINIA B．PETERS244

Ⅳ．Cytopathology＆ALBERT J．DALTON246

Ⅴ．Histopathology＆THELMA B．DUNN248

Ⅵ．Protozoa and Cancer＆THEODORE HAUSCHKA250

Ⅶ．Protozoan Metabolite Project＆CHARLES W．REES258

Ⅷ．Nuclear Changes Produced by S．Marcescens (B．Prodigiosus) Polysaccharide＆IRENE COREY DILLER260

Ⅸ．Temperature Changes Produced in Mice with S．Marcescens Polysaccharide＆LYLE V．BECK265

Ⅹ．Preparation of Polysaccharide Solutions for Clinical Use and Tissue Culture Experiments＆JANE ROYLE MCCONNELL271

Ⅺ．Reactions of Patients and of Tumors to Injection of S．Marcescens Polysaccharide in Eight Cases of Malignant Disease＆A．LEON HOLLOMAN273

Ⅻ．Reactions of Patients to Injection of S．Marcescens Polysaccharide in Nine Further Cases of Malignant Disease＆R．OAKEY277

ⅩⅢ．Clinical Pathological Considerations，and Resume＆STANLEY P．REIMANN278

The Relation Between Chemical Constitution and Biological Action of the Nitrogen Mustards＆FREDERICK S．PHILIPS AND ALFRED GILMAN285

Experimental Observations on the Use of the Nitrogen Mustards in the Treatment of Neoplastic Disease．D．A．Karnofsky，＆J．H．BURCHENAL，R．A．ORMSBEE，I．CORNMAN AND C．P．RHOADS293

The Clinical Application of Methyl-Bis (β-Chloroethyl) Amine Hydrochloride to the Treatment of Lymphomas and Allied Dyscrasias＆CHARLES L．SPURR，LEON-0．JACOB-SON，TAYLOR R．SMITH AND E．S．GUZMAN BARRON306

An Evaluation of Methyl-Bis(β-Chloroethyl) Amine Hydrochloride(Nitrogen Mustards)in the Treatment of Lymphomas，Leukemia and Allied Diseases． D．A．KARNOFSKY，L．F．CRAVER，C．P．RHOADS and J．C．ABELS，with the technical assistance of MYRTLE E．MCELROY……319

Use of Methyl-Bis(β-Chloroethyl) Amine Hydrochloride and Tris(β-Chloroethyl)Amine Hydrochloride(＂Nitrogen-Mustards＂) in the Therapy of Hodgkin’s Disease，Lymphosarcoma，Leukemia and Certain Allied and Miscellaneous Disorders．Louis S． GOODMAN，MAXWELL M．WINTROBE，MARGARET T．MCLENNAN，WILLIAM DAMESHEK，MORTON J． GOODMAN and MAJOR ALFRED GILMAN338

Clinical Experiences with Nitrogen Mustard Therapy＆MAXWELL M．WINTROBE，MARGARET T．MCLENNAN and CHARLES M．HUGULEY，JR347

Some Effects of Sulfur and Nitrogen Mustards on Cell Nuclei in Mammalian Cornea＆JONAS S．FRIEDENWALD，WILHELM BUSCHKE，ROY 0．SCHOLZ AND SYLVIA G．MOSES358

Anti-Androgenic Treatment of Prostatic Carcinoma in Man＆CHARLES HUGGINS379

The Treatment of Blood Dyscrasias，Lymphomas，and other Malignant Diseases with Radioactive Phosphorus：Clinical and Experimental Results＆EDWARD H．REINHARD AND NATHAN A．WOMACK384

A Further Report on the Action of Urethane in Leukemia＆EDITH PATERSON，INEZ APTHOMAS，ALEXANDER HADDOW AND JEAN M．WATKINSON401

Effects of Urethane upon Acute Lymphatic Leukemia in a Dog＆H．B．PARRY AND J．R．M．INNES416

Treatment of Leukemia with 9，10-Dimethyl-l，2-Benzanthracene＆J．ENGELBRETH-HOLM AND S．STAMER419

Administration of Oil-Soluble Organo-Metallic Compounds in Malignancy＆CHARLES F．GESCHICKTER AND E．EMMET REID431