《chemical induction of cancer P250》求取 ⇩

INTRODUCTION1

Ⅰ．STRUCTURE AND ACTIVITY9

Ⅱ．BIOLOGICAL ASPECTS OF TUMOUR INDUCTION38

General Characteristics of Tumours38

Pathology of Induced Tumours42

Sex Differences and Tumour Induction51

Age and Tumour Induction53

Hereditary Differences and Tumour Induction54

Species Differences and Tumour Induction59

Influence of the Diet on Tumour Induction62

Ⅲ．TEST METHODS68

Mode of Administration68

Solvent Effects70

Anti-and Co-carcinogenesis75

Dosage，Latent Period，Tumour Incidence and the Carcinogenic Index80

Ⅳ．THEORIES OF THE MODE OF ACTION OF CARCINOGENS96

Ⅴ．BIOGENETIC RELATIONSHIPS132

Ⅵ．METABOLISM OF CARCINOGENIC HYDROCARBONS153

Ⅶ．CARCINOGENIC AZO COMPOUNDS174

Ⅷ．CARCINOGENIC AROMATIC AMINES AND DERIVATIVES210

APPENDIX Ⅰ．Some Chemical Carcinogens222

APPENDIX Ⅱ．Inhibition of Tumour Growth and Possibilities of Tumour Chemotherapy227

GENERAL REVIEWS238

INDEX239

PLATES42

Ⅰ．Keratinising skin carcinoma in mouse，induced by benzpyrene42

Ⅱ．Keratinising skin carcinoma in mouse，induced by benzpyrene．A more advanced stage than previous plate43

Ⅲ．Spindle-celled sarcoma induced in a Strong A mouse by 0．25 mg．methylcholanthrene44

Ⅳ．Adenocarcinoma of lung induced by methylcholanthrene in a Strong A mouse45

Ⅴ．Liver of Wistar rat fed dimethylaminoazobenzene with low protein diet for four months．Cholangioma showing a typical formation of new ducts48