《中国医学院士文库：刘志红院士集》求取 ⇩

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第一部分奋斗历程1

医学高峰的眺望者——记国际著名肾脏病学专家、中国工程院院士刘志红3

第二部分学术贡献21

一、刘志红院士的学术成就与学术思想23

二、刘志红院士的主要学术论文34

（一）肾脏病学的发展34

Nephrology in China35

中国肾脏病诊治三十年回顾与展望40

系统生物学——推动肾脏病临床研究的新动力46

转化医学：医学模式的转化，医学发展的方向49

（二）IgA肾病51

Epidemiologic Data of Renal Diseases from a Single Unit in China：Analysis Based on 13 519 Renal Biopsies52

Interleukin-1Receptor Antagonist Allele：Is It a Genetic Link between Henoch-Schonlein Nephritis and IgA Nephropathy？58

Long-term Renal Survival and Related Risk Factors in Patients with IgA Nephro- pathy：Results from a Cohort of 1155 Cases in a Chinese Adult Population63

A Multicenter Application and Evaluation of the Oxford Classification of IgA Nephropathy in Adult Chinese Patients72

Corticosteroid Therapy in IgA Nephropathy with Minimal Change-like Lesions： a Single-centre Cohort Study80

MiR-223 Downregulation Promotes Glomerular Endothelial Cell Activation by Upregulating Importin α4 and α5 in IgA Nephropathy86

Long-Term Outcome of IgA Nephropathy Patients with Recurrent Macroscopic Hematuria99

（三）狼疮性肾炎106

Multitarget Therapy for Induction Treatment of Lupus Nephritis A Randomized， Controlled Trial107

Sex Differences in Estrogen Receptor Gene Polymorphism and Its Association with Lupus Nephritis in Chinese118

Epistatic Effect of Plasminogen Activator Inhibitor 1and β3-Fibrinogen Genes on Risk of Glomerular Microthrombosis in Lupus Nephritis124

Association of Interleukin-10 Gene-592 A/C Polymorphism with the Clinical and Pathological Diversity of Lupus Nephritis133

Evaluation of Renal Vascular Lesions Using Circulating Endothelial Cells in Patients with Lupus Nephritis139

Circulating Thrombomodulin and Vascular Cell Adhesion Molecule-1and Renal Vascular Lesion in Patients with Lupus Nephritis146

Peritubular Capillary C4d deposition in Lupus Nephritis Different from Antibody-mediated Renal Rejection152

Effects of Mycophenolic Acid on Endothelial Cells157

（四）糖尿病肾病165

Glucose Transporter （GLUT1）Allele （Xba Ⅰ-）Associated with Nephropathy in Non-insulin-dependent Diabetes Mellitus166

Amylin Deposition in the Kidney of Patients with Diabetic Nephropathy171

Rhein Protects Pancreatic β-Cells from Dynamin-Related Protein-1-Mediated Mitochondrial Fission and Cell Apoptosis Under Hyperglycemia178

Evaluation of Podocyte Lesion in Patients with Diabetic Nephropathy：Wilms’ Tumor-1Protein Used as a Podocyte Marker189

Rhein Improves Renal Lesion and Ameliorates Dyslipidemia in db/db Mice with Diabetic Nephropathy196

Combined Therapy of Rhein and Benazepril on the Treatment of Diabetic Nephro- pathy in db/db Mice203

Treatment of Diabetic Nephropathy with Tripterygium Wilfordii Hook F Extract： a Prospective，Randomized，Controlled Clinical Trial209

Treatment of db/db Diabetic Mice with Triptolide：a Novel Therapy for Diabetic Nephropathy218

Renal Histologic Changes and the Outcome in Patients with Diabetic Nephropathy228

（五）肥胖相关性肾病238

Obesity-Related Glomerulopathy：Insights from Gene Expression Profiles of the Glomeruli Derived from Renal Biopsy Samples239

Podocyte Lesions in Patients with Obesity-Related Glomerulopathy247

Obesity-Related Glomerulopathy in China：a Case Series of 90 Patients253

Roles of Mast Cells and Monocyte Chemoattractant Protein-1 in the Renal Injury of Obesity-related Glomerulopathy260

Obesity-Related Glomerulopathy：Body Mass Index and Proteinuria266

（六）足细胞及足细胞病276

Downregulation of MicroRNA-30 Facilitates Podocyte Injury and Is Prevented by Glucocorticoids277

Anti-Phospholipase A2 Receptor Antibody in Membranous Nephropathy284

Triptolide Protects Podocytes from Puromycin Aminonucleoside Induced Injury in vivo and in vitro291

Triptolide Reduces Proteinuria in Experimental Membranous Nephropathy and Protects Against C5b-9-induced Podocyte Injury in vitro300

Etiology and Clinical Characteristics of Membranous Nephropathy in Chinese Patients309

Long-term Outcome and Prognostic Factors of Idiopathic Membranous Nephro- pathy in the Chinese Population317

Mercury-Induced Membranous Nephropathy： Clinical and Pathological Features326

Thromboembolic Complications in Membranous Nephropathy Patients with Nephrotic Syndrome-a Prospective Study332

The Clinical Course and Long -Term Outcome of Primary Focal Segmental Glomerulosclerosis in Chinese Adults338

Evaluation of MicroRNAs miR-196a，miR-30a-5P，and miR-490 as Biomarkers of Disease Activity among Patients with FSGS346

Relationship between Serum Soluble Urokinase Plasminogen Activator Receptor Level and Steroid Responsiveness in FSGS354

Plasma Micro RNA-186 and Proteinuria in Focal Segmental Glomerulosclerosis363

（七）遗传性肾病375

Spectrum of Clinical Features and Type Ⅳ Collagen α-Chain Distribution in Chinese Patients with Alport Syndrome376

Quantitative Analysis of Type Ⅳ Collagen Subchains in the Glomerular Basement Membrane of Patients with Alport Syndrome with Confocal Microscopy386

A Complete Genomic Analysis of the Apolipoprotein E Gene in Chinese Patients with Lipoprotein Glomerulopathy397

Fabry Disease：Renal Biopsy-Proven Cases from China402

（八）血液净化和肾移植410

Influence of CYP3A5 and MDR1Polymorphisms on Tacrolimus Concentration in the Early Stage after Renal Transplantation411

Endothelial Dysfunction in Patients with Severe Acute Pancreatitis：Improved by Continuous Blood Purification Therapy416

Recipient-Derived Cells in the Tissue Repair of Renal Allografts423

Improvement of Monocyte Function and Immune Homeostasis by High Volume Continuous Venovenous Hemofiltration in Patients with Severe Acute Pancreatitis427

三、刘志红院士的主要学术著作434

中国肾脏病学（上、下册）434

肾脏病临床集锦——精选病例100例436

Podocytopathy439

慢性肾脏病矿物质与骨异常诊治指导442

肾脏病科普丛书（一套四册）444

四、刘志红院士的重要学术报告447

脂蛋白肾病：新的疾病，新的启迪448

马兜铃酸肾病：一个虽被认识但未解决的问题451

积极应对继发性肾脏病带来的挑战455

局灶节段性肾小球硬化的诊断：摆脱组织形态学束缚的努力457

足细胞病的治疗：免疫抑制剂，还是足细胞保护460