《AN INTRODUCTION TO GENETIC ANALYSIS SECOND EDITION》
作者 | DAVID T.SUZUKI ANTHONY J.F.GR 编者 |
---|---|
出版 | W.H.FREEMAN AND COMPANY |
参考页数 | 911 |
出版时间 | 1981(求助前请核对) 目录预览 |
ISBN号 | 0716712636 — 求助条款 |
PDF编号 | 813686658(仅供预览,未存储实际文件) |
求助格式 | 扫描PDF(若分多册发行,每次仅能受理1册) |

Introduction1
Genetics in Biology1
Genetics and Human Affairs2
Chapter 1Gene and Organism9
Gene and Environment11
Genotype and Phenotype14
The Norm of Reaction15
Developmental Noise19
Variation Is the Raw Material of Genetic Analysis21
Summary23
Chapter 2Mendelism27
Mendel’s Experiments28
Simple Mendelian Genetics in Humans45
Simple Mendelian Genetics in Agriculture48
The Origin of Variants51
Genetic Dissection52
Summary53
Problems54
Chapter 3Chromosome Theory of Inheritance63
Mitosis and Meiosis63
The Chromosome Theory of Heredity68
Sex Chromosomes in Other Species82
The Chromosome Theory in Review86
Mendelian Genetics in Less Familiar Sexual Cycles88
Summary96
Problems97
Chapter 4Extensions to Mendelian Analysis103
Variations on Dominance Relations104
Multiple Alleles107
Lethal Genes113
Several Genes Affecting the Same Character116
Penetrance and Expressivity122
Summary125
Problems126
Chapter 5Linkage135
The Discovery of Linkage135
Recombination140
Linkage Symbolism144
Linkage of Genes on the X Chromosome144
Linkage Maps145
Three-Point Testcross for Linkage Detection148
Double Crossovers152
The x2 Test158
Early Thoughts on the Nature of Crossing Over161
Linkage Mapping by Recombination in Humans167
Summary169
Problems169
Chapter 6Advanced Transmission Genetics177
Mapping Functions177
Tetrad Analysis184
Mitotic Segregation and Recombination199
Mapping Human Chromosomes205
Summary210
Problems210
Chapter 7Gene Mutation219
Somatic Versus Germinal Mutation220
Types of Mutations222
The Usefulness of Mutations226
Mutation Detection Systems226
Selective Systems229
Mutation Induction by Mutagens242
The Mutant Hunt245
Mutation Breeding247
Summary250
Problems250
Chapter 8Chromosome Mutation255
Cytological Properties of Chromosomes256
Changes in Chromosome Structure260
Changes in Chromosome Number284
Chromosome Mechanics in Plant Breeding302
Summary304
Problems305
Chapter 9Recombination in Bacteria and Their Viruses317
Bacterial Conjugation318
Bacterial Transformation339
Phage Genetics343
Transduction356
Summary362
Problems363
Chapter 10The Nature of the Gene371
Position Effect373
Intragenic Recombination373
Intragenic Complementation380
How Genes Work385
Gene-Protein Relations395
Temperature-Sensitive Alleles410
Genetic Dissection of Genes411
Summary411
Problems412
Chapter 11DNA Structure425
The Structure of DNA426
Replication of DNA434
DNA and the Gene452
The Genetic Code455
Alternative DNA Models461
Summary462
Problems463
Chapter 12DNA Function467
Transcription468
Translation472
Cracking the Code480
Summary492
Problems493
Chapter 13Manipulation of DNA501
The Power of Base Complementarity502
Genetic Engineering526
Summary549
Problems550
Chapter 14The Structure and Function of Chromosomes555
Constitutive Heterochromatin556
Facultative Heterochromatin563
Eukaryote Gene Function and Organization572
Genes with Related Functions585
Summary656
Problems656
Chapter 15Organelle Genes615
Variegation in Leaves of Higher Plants618
Poky Neurospora622
The Heterokaryon Test624
Shell Coiling in Snails: A Red Herring624
Extranuclear Genes in Chlamydomonas626
Extranuclear Genes in Bakers’ Yeast637
How Many Copies?653
Other Examples of Extranuclear Inheritance653
Summary656
Problems656
Chapter 16Mechanisms of Genetic Change663
Gene Mutation664
Recombination690
Transposable Genetic Elements703
Summary720
Problems721
Chapter 17Developmental Genetics727
Development as a Regulated Process727
Differentiation and Variable Gene Activity741
Immunogenetics: The Immune System as a Developmental Model762
Developmental Genetics of Drosophila775
Summary797
Problems798
Chapter 18Quantitative Genetics807
Some Basic Statistical Notions809
Genotypes and Phenotypic Distribution818
Norm of Reaction and Phenotypic Distribution821
The Heritability of a Trait823
Determining Norms of Reaction826
Quantifying Heritability831
Counting and Locating the Genes837
Gene Action840
More on Analyzing Variance840
Summary847
Problems848
Chapter 19Population Genetics853
Darwin’s Revolution854
Variation and Its Modulation855
The Sources of Variation867
The Effect of Sexual Reproduction on Variation873
Selection881
Balanced Polymorphism891
Multiple Adaptive Peaks894
Artificial Selection897
Random Events899
A Synthesis of Forces901
The Origin of Species905
Summary906
Problems908
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