《METABOLOMICS THE FRONTIER OF SYSTEMS BIOLOGY》

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出版 SPRINGER
参考页数 256
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METABOLOMICS THE FRONTIER OF SYSTEMS BIOLOGY PDF电子版封面 4431251219

Part Ⅰ.Introduction1

Chapter 1：OverviewM.Tomita1

Part Ⅱ.Analytical Methods for Metabolome Sciences7

Chapter 2：Development and Application of Capillary Electrophoresis-Mass Spectrometry Methods to MetabolomicsT.Soga7

Chapter 3：Application of Electrospray Ionization Mass Spectrometry for MetabolomicsR.Taguchi25

Chapter 4：High-Performance Liquid Chromatography and Liquid Chromatography/Mass Spectrometry Analyses of Metabolites in MicroorganismsH.Miyano37

Chapter 5：Metabolome Profiling of Human Urine with Capillary Gas Chromatography/Mass SpectrometryT.Kuhara53

Chapter 6：Metabolic Profiling by Fourier-Transform Ion Cyclotron Resonance Mass Spectrometry（FT-ICR-MS）and Electrospray Ionization Quadrupole Time-Of-Flight Mass Spectrometry（ESI-Q-TOF-MS）K.Hirayama75

Chapter 7：Metabolome Analysis by Capillary ElectrophoresisL.Jia and S.Terabe91

Chapter 8：High-Performance Liquid Chromatography for Metabolomics：High-Efficiency Separations Utilizing Monolithic Silica ColumnsT.Ikegami，H.Kobayashi，H.Kimura，V.V.Tolstikov，O.Fiehn，and N.Tanaka107

Part Ⅲ.Applications of Metabolome Analysis to Biosciences127

Chapter 9：Combined Analysis of Metabolome and Transcriptome：Catabolism in Bacillus subtilisT.Nishioka，K.Matsuda，and Y.Fujita127

Chapter 10：Metabolomics in Arabidopsis thalianaK.Saito141

Chapter 11：Lipidomics：Metabolic Analysis of PhospholipidsR.Taguchi155

Chapter 12：Chemical Diagnosis of Inborn Errors of Metabolism and Metabolome Analysis of Urine by Capillary Gas Chromatography/Mass SpectrometryT.Kuhara167

Part Ⅳ.Metabolome Informatics193

Chapter 13：Introduction to the ARM Database：Database on Chemical Transformations in Metabolism for Tracing PathwaysM.Arita193

Chapter 14：The Genome-Based E-CELL Modeling（GEM）SystemK.Arakawa，Y.Yamada，K.Shinoda，Y.Nakayama，and M.Tomita211

Chapter 15：Hybrid Dynamic/Static Method for Large-Scale Simulation of Metabolism and its Implementation to the E-CELLSystemY.Nakayama221

Part Ⅴ.Metabolomics and Medical Sciences233

Chapter 16：Metabolomics and Medical SciencesT.Nishioka233

Index245

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