《METABOLOMICS THE FRONTIER OF SYSTEMS BIOLOGY》求取 ⇩

Part Ⅰ.Introduction1

Chapter 1:OverviewM.Tomita1

Part Ⅱ.Analytical Methods for Metabolome Sciences7

Chapter 2:Development and Application of Capillary Electrophoresis-Mass Spectrometry Methods to MetabolomicsT.Soga7

Chapter 3:Application of Electrospray Ionization Mass Spectrometry for MetabolomicsR.Taguchi25

Chapter 4:High-Performance Liquid Chromatography and Liquid Chromatography/Mass Spectrometry Analyses of Metabolites in MicroorganismsH.Miyano37

Chapter 5:Metabolome Profiling of Human Urine with Capillary Gas Chromatography/Mass SpectrometryT.Kuhara53

Chapter 6:Metabolic Profiling by Fourier-Transform Ion Cyclotron Resonance Mass Spectrometry(FT-ICR-MS)and Electrospray Ionization Quadrupole Time-Of-Flight Mass Spectrometry(ESI-Q-TOF-MS)K.Hirayama75

Chapter 7:Metabolome Analysis by Capillary ElectrophoresisL.Jia and S.Terabe91

Chapter 8:High-Performance Liquid Chromatography for Metabolomics:High-Efficiency Separations Utilizing Monolithic Silica ColumnsT.Ikegami,H.Kobayashi,H.Kimura,V.V.Tolstikov,O.Fiehn,and N.Tanaka107

Part Ⅲ.Applications of Metabolome Analysis to Biosciences127

Chapter 9:Combined Analysis of Metabolome and Transcriptome:Catabolism in Bacillus subtilisT.Nishioka,K.Matsuda,and Y.Fujita127

Chapter 10:Metabolomics in Arabidopsis thalianaK.Saito141

Chapter 11:Lipidomics:Metabolic Analysis of PhospholipidsR.Taguchi155

Chapter 12:Chemical Diagnosis of Inborn Errors of Metabolism and Metabolome Analysis of Urine by Capillary Gas Chromatography/Mass SpectrometryT.Kuhara167

Part Ⅳ.Metabolome Informatics193

Chapter 13:Introduction to the ARM Database:Database on Chemical Transformations in Metabolism for Tracing PathwaysM.Arita193

Chapter 14:The Genome-Based E-CELL Modeling(GEM)SystemK.Arakawa,Y.Yamada,K.Shinoda,Y.Nakayama,and M.Tomita211

Chapter 15:Hybrid Dynamic/Static Method for Large-Scale Simulation of Metabolism and its Implementation to the E-CELLSystemY.Nakayama221

Part Ⅴ.Metabolomics and Medical Sciences233

Chapter 16:Metabolomics and Medical SciencesT.Nishioka233

Index245

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