《Blood Platelets》

Introduction PLATELETS IN HEMOSTASIS AND THROMBOSIS＆Chairman，WALTER H．SEEGERS1

1．The Blood Platelets—Past，Present and Future＆Leandro M．Tocantins3

2．Platelets in the Peripheral Circulation＆Herbert J．Berman and George P．Fulton7

Ⅰ．PLATELETS IN BLOOD VESSEL INTEGRITY21

3．Morphology and Dynamics of Endothelium＆Rudolf Altschul23

4．Capillary Resistance and Its Relation to Bleeding＆Jeno Kramar41

5．Studies on Hemostasis in Vivo＆Walter O．Cruz49

GE ERAL DISCUSSION，＆Wissler，Fulton，Tocantins，Cruz，Ungar，Sharnoff，Thomas，Kramár61

Ⅱ．PLATELET CLUMPING＆Chairman，C．LOCKARD CONLEY65

6．Platelet(Viscous)Metamorphosis＆Alan A．Sharp67

7．Morphological Studies on the Mechanism of Viscous Metamorphosis of Platelets＆Robert L．Rosenthal and Soonu B．Vyas89

8．Phase Microscopy and the Enumeration of Blood Platelets＆Robert Feissly99

9．Natural Thrombocyte Agglutinating Systems：Thrombocyte Agglutinating Factors(TAg and TAg＇)in Plasma＆R．G．Mason，E．Carwile LeRoy and Kenneth M Brinkhous111

10．In Vitro Platelet Aggregation in Relation to Met？s，Macromolecules and Surfaces＆Charles E．Brambel123

Ⅲ．PHYSIOLOGY AND PATHOLOGY OF HEMOSTASIS＆Chairman，C．LOCKARD CONLEY133

11．Multiple Factors in Hemorrhage＆Louis B．Jaques135

DESIGNATED DISCUSSION，＆Marjorie B．Zucker141

GENERAL DISCUSSION，＆Roskam，Chandler，Bergsagel，Cruz，Rosenthal，Sharp，Conley， Brinkhous，Gollub，Jaques，Harrington，Brambel，Surgenor145

Ⅳ．ROLE OF PLATELETS IN THROMBOSIS＆Chairman，ROBERT W．WISSLER 151

12．Role of Platelets in the Formation of a Hemostatic Plug＆Jacques Roskam153

13．Dietary Lipids and the Clotting Mechanism with Particular Reference to Lysis＆Wilbur A．Thomas163

14．The Influence of Induced Atherosclerosis on Calcium，Phosphorus and Sulfate in the Arterial Wall＆Albert J．Boyle，D．S．McCann，D．T．Forman and H．Kagen173

15．Lipids，Platelets and Atherosclerosis＆James F．Mustard，H．G．Downie，E．A．Murphy and H．C．Rowsell191

DESIGNATED DISCUSSION，＆Robert W．Wissler205

GENERAL DISCUSSION，＆Pirkle，McDonald，Merskey，Thomas，Deutsch，Mandel，Spaet，Mustard，Cruz209

Ⅴ．PLATELETS IN THE PHYSIOLOGY OF HEMOSTASIS，WITH PARTICULAR REFERENCE TO BLEEDING TIME＆Chairman，RAYMOND W．MONTO217

DESIGNATED DISCUSSION，＆Monto，Spaet，Roskam，Fulton，Cruz，Jaques，Sharp，Lüscher219

GENERAL DISCUSSION，＆Quick，Sharp，Maupin，Weiner，Spaet，Roskam，Fulton，Cruz，Jaques，Snart，Kupfer，Jacobson，Friedman，Sharnoff，Monto230

Ⅵ．PHYSIOLOGICAL AND BIOCHEMICAL MECHANISMS OF PLATELETS IN BLOOD COAGULATION＆Chairman，ARMAND J．QUICK239

6．Platelet Fractions and Prothrombin Activation＆Walter H．Seegers241

7．The Synthesis of Glycerolphosphatides＆Erich Baer253

18．The Platelet Lipids：Their Identification，Quantification and Behavior in Clotting Systems in Vitro＆Stanley B．Troup，Claude F．Reed，Guido V．Marinetti and Scott N．Swisher265

19．The Thromboplastic Activity of Some Soybean Phospholipids＆William J．Williams277

20．Biophysical Aspects of Platelet Reaction Mechanisms in Clotting＆Douglas M．Surgenor and Donald F．Hoelzl Wallach289

21．The Lipids of Human Erythrocytes and Platelets and Their Effects on Thromboplastin Formation＆Percy Barkhan，Melvin J．Silver and Louise M．O＇Keefe303

GENERAL DISCUSSION，＆Gross，Wissler，Surgenor，Born，Vroman，Caen，O＇Brien，Marcus，Davis319

Ⅶ．PLATELET FRACTIONS＆Chairman，SHIRLEY A．JOHNSON327

22．The Antifibrinolytic Activity of Platelets＆Norma Alkjaersig329

23．Studies on Platelet Factor 4＆Erwin Deutsch and Walter Kain337

24．The Nature of the Lipoprotein of Human Platelets and Erythrocytes＆George Y．Shinowara347

GENERAL DISCUSSION，＆Quick，Beller，O＇Brien，Shanberge，Dreskin，Jürgens，Henstell，Alkjaersig，Deutsch，Shinowara357

Ⅷ．METABOLISM OF PLATELETS＆Chairman，KENNETH M．BRINKHOUS363

25．The Breakdown of Phospholipids and of Other Phosphorus Compounds During Coagulation of Platelet-rich Plasma＆Gustav V．R．Born and M．Peter Esnouf365

26．Changes in Platelet Adenosine Triphosphate Concentration and Phosphate Distribution During Viscous Metamorphosis and Clot Retraction＆Marjorie B．Zucker and Jennie Borrelli383

27．Studies on the Uptake of Serotonin by Platelets＆Herbert Weissbach and Betty G．Redfield393

28．Metabolic Aspects of Normal and Pathological Platelets＆Rudolf Gross407

29．Effects of Sulfhydryl Inhibitors on Structural Stability of Platelets＆J．Leo Koppel423

GENERAL DISCUSSION，＆Hartert，Lasch，Shinowara，Ungar，Born，Zucker，Harrington430

Ⅸ．CLOT RETRACTION OF PLATELETS＆Chairman，KENNETH M．BRINKHOUS435

30．Platelets in Clot Retraction＆C．Lockard Conley437

31．Retraction Activity of the Platelets： Biochemical Background and Physiological Significance＆Ernst F．Lüscher445

32．Time Lapse Photography of Clot Retraction＆Giorgio Ballerini and Walter H．Seegers455

GENERAL DISCUSSION，＆Baldini，Cruz，Hartert，Zucker，Lüscher，Beller，Weissbach，Seegers456

Ⅹ．BANQUET SPEECH＆Chairman，ROBERT C．HORN，JR461

33．The Mystery of Indo-European Expansion＆Clark Hopkins463

Ⅺ．THROMBOCYTOPENIC BLEEDING＆Chairman，MAXWELL M．WINTROBE473

34．Evaluation of the Degree of Bleeding in Thrombocytopenic States＆Dudley P．Jackson475

35．Thrombocytopenic Bleeding and Preservation of Platelets＆Phin Cohen and Frank H．Gardner485

36．Platelets and Heparin＆Robert C Hartmann499

GENERAL DISCUSSION，＆Baldini，Weiss，Weiner，Lasch，Ebaugh，Caen，Gross，Maupin，Dentsch，Lüscher，Tullis，Jackson，Gardner，Hartmann，Johnson512

Ⅻ．ALTERED PLATELET FUNCTION＆Chairman，LEANDRO M．TOCANTINS523

37．Specific Platelet Alterations Related to Hematological Disorders＆Shirley A．Johnson，Raymond W．Monto and John W．Rebuck523

38．Volumetric and Ultrastructural Studies of Abnormal Platelets＆John W．Rebuck，Jeanne M．Riddle，Morden G．Brown，Shirley A．Johnson and Raymond W．Monto533

39．The Qualitative Platelet Diseases＆Orhan N．Ulutin553

40．Some Qualitative and Quantitative Aspects of Platelet Function in Normal，Thrombocytopenic，and Thrombocytopathic States＆Helen Czemobilsky and Benjamin Alexander565

GENERAL DISCUSSION，＆Tocantins，Schmidt，Braunsteiner，Marcus，Zucker，Henstell，Wall，Merskey，Deutsch，Spaet，Johnson，Rebuck，Ulutin585

ⅩⅢ．HEMATOPOIETIC ASPECTS AND PHYSICAL PROPERTIES OF PLATELETS＆Chairman，JOHN W．REBUCK593

41．Studies on the Origin，Production and Destruction of Platelets＆Eugene P．Cronkite，Victor P．Bond，Theodor M．Fliedner，Donald A．Paglia and Emil R．Adamik595

42．Biodynamics of Thrombopoiesis＆Riojun Kinosita and Susumn Ohno611

43．Electron Microscopy of Blood Platelets＆Herbert Braunsteiner617

44．Thrombokinetics＆Clement A．Finch629

GENERAL DISCUSSION，＆Rebuck，Schulman， Sharnoff，Baldini，Cooney，Wood，Schroeder，Gardner，Cronkite，Finch，Kinosita634

ⅩⅣ．LABELING，LIFE SPAN AND PRESERVATION＆Chairman，CARL V．MOORE641

45．Platelet Labeling with Radioisotopes and in Vivo Platelet Survival＆T．T．Odell，Jr643

46．Survival of Platelets Transfused into Thrombocytopenic Recipients＆Julius R．Krevans651

ⅩⅤ．IMMUNOLOGICAL ASPECTS OF PLATELETS＆Chairman，CARL V．MOORE657

47．Immune Reactions of Platelets＆William J．Harrington and Grace Arimura659

48．Mechanisms of Immunogenic Platelet Damage＆Peter A．Miescber and Fred Gorstein671

49．The Identification and Isolation of Antiplatelet Proteins＆James L．Tullis679

50．Use of the Fluorescent Antibody Technique in the Detection of Platelet Antibodies＆Charles C．Sprague689

GENERAL DISCUSSION，＆Pisciotta，Baldini，Odell696

51．Closing Remarks＆Carl V．Moore699

Index701