《Table 2 Predisposing causes of portal vein thrombosis》

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《Is porto sinusoidal vascular disease to be actively searched in patients with portal vein thrombosis》

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LLAC:Lupus-like anticoagulant；ELISA:Enzyme-linked immunosorbent assay；BMI:Body mass index；CMV，Cytomegalovirus；HCG:Human chorionic gonadotropin；Ig:Immunoglobulin；TIPS:Transjugular portosystemic intrahepatic shunt.

In conclusion，PSVD is probably a not so rare condition that should be actively searched not only by the hepatologists in the patients with signs of portal hypertension but also by the specialists who manage the patients affected by diseases associated with PSVD.Among the conditions associated with PSVD，PVT could be also included，and the suspicion of a pre-existing and missed PSVD should arise in any patient with PVT included（and maybe especially）in those affected by a prothrombotic state.However，more studies are needed to clarify the distinctive features of PSVD and PVT both histologically and elastographically，and new studies are needed to clarify the indications and the benefits of anticoagulant therapy in patients affected by PSVD.