《Table 1 Diseases associated to porto sinusoidal vascular liver disease》

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《Is porto sinusoidal vascular disease to be actively searched in patients with portal vein thrombosis》

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The strong relationship between PSVD，hypercoagulability and incidence of PVT led to the hypothesis that a subset of patients with acute or chronic PVT could be affected by a pre-existing，undiagnosed PSVD.Actually，despite an active search[8]of local or systemic predisposing conditions（Table 2），the cause of PVT is not recognizable in up to 25%of the patients.Moreover，in patients in whom a PVT is diagnosed，the evidence of a prothrombotic state usually leads to the diagnosis of a PVT secondary to that condition without taking into consideration the possibility of a pre-existing and undiagnosed PSVD.The possibility of missing a diagnosis of PSVD in a patient with PVT，especially if acute，may have relevant clinical consequences.