《Table 2Maximum residues limits (MRLs) of mycotoxins》

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《"Extrinsic harmful residues in Chinese herbal medicines: types,detection, and safety evaluation"》

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EC，European Commission Regulation；EP，European Pharmacopoeia 9th；BP，British Pharmacopoeia（2017）；Ch P，Chinese Pharmacopoeia（2015）；JP，Japanese Pharmacopoeia 17th；USP，United States Pharmacopeia 40th；GSMPP，Green standards of medicinal plants and prep

It is difficult to detect mycotoxins in the complex matrix of CHMs because the MRLs of mycotoxins are very low.The matrices of CHMs are complex，so there are some limitations that the sample testing process and detection methods in agricultural products are directly applied.Nowadays a variety of purification methods have been developed for the complex matrix of CHMs，including solid-phase extraction（SPE），liquid-liquid extraction，chemical adsorption，“quick，easy，cheap，effective，rugged and safe”（Qu ECh ERS），and immunoaffinity column（IAC）（Kong et al.，2014；Wen，Kong，Hu，Wang，&Yang，2014；Zhang et al.，2017） .Table 3 showed the mycotoxin pollution status of CHMs that may provide a reference for the safety of CHMs on the early warning of mycotoxins contamination and reduce the risk of mycotoxins in clinic.