《Tab.1 Screening of conditions of Suzuki reaction catalyzed by 1 and 2》

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《基于纳米二氧化硅与MCM-41的两种多相钯催化剂的合成及其在Suzuki反应中的应用（英文）》

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*Molar percentage of Pd，0.11%mol；GC，Gas chromatograph yield.

After fully characterizing the catalysts，we further investigated their catalytic activities in Suzuki reaction.To optimize the reaction conditions，the Suzuki coupling of bromobenzene（1 mmol）with phenyl boronic acid（1 mmol）was examined using different catalysts and solvents at a temperature range of 25～60℃（Tab.1）.In these experiments，only environment-friendly ethanol and water were used as solvents.When the reaction was carried out without catalyst，there was no product（Entry 1）.Catalyst 1 was selected as the main condition optimization object.In the first stage，different bases and solvents were used，and the results showed that the yields of the reaction were low at room temperature（Entry 2～9）.In the two cases of Entry4（Et OH，Me ONa）and Entry 7（Et OH/H2O v/v=3/2，K2CO3），the yields are slightly higher.In the second stage，the reaction temperature was increased from room temperature to 60℃.The best result wasobtained when EtOH/H2O（v/v=3/2）was employed as solvent and K2CO3was employed as base.In the third stage，catalyst 2 was used in the same optimum conditions as catalyst 1，and it also achieved wonderful results（Entry 16）.