《Table 2 Status of Treponema pallidum A2058G and A2059G mutations in azithromycin-or BPG-treated pat

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《Relationship between the high frequency of 23S rRNA point mutations in Treponema pallidum and low serological response rate to azithromycin treatment in China》

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Chi-squared tests were conducted，and P-values of<0.05 wereconsidered to indicate statistical significance.BPG，benzathinepenicillin G.

The A2058G and A2059G mutation statuses in the azithromycin and BPG groups are shown in Table 2.Of the 89 DNA samples obtained from the azithromycin group that were positive for the tpp47 gene，83（93.3%）were positive for a mutation，including 71（79.8%）positive for A2058G and 12（20.2%）positive for A2059G.Of these 83 samples，51（61.4%）were collected from chancres and 32 from condyloma lata and mucosal lesions.Of the 98 equivalent samples obtained from the BPG group，89（90.8%）were positive for one of the two mutations；82（83.7%）of these 89 patients had an A2058G mutation，and 7（7.1%）had an A2059G mutation.There was no significant difference in the proportions of the two mutations between the azithromycin and BPG groups（P>0.05）.