《Table 1Baseline characteristics of patients (n=44) .》

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《"KML001, an arsenic compound, as salvage chemotherapy in refractory biliary tract cancers: A prospective study"》

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SD:standard deviation；CCC:cholangiocarcinoma；ECOG PS:Eastern Cooperative Oncology Group performance status.

Forty-four patients（21 women，23 men）were enrolled between November 2011 and October 2014.Characteristics of these patients are summarized in Table 1.The mean age was 61.5±8.9 years.There were 17 patients（38.6%）with intrahepatic cholangiocarcinoma，nine patients（20.5%）with perihilar cholangiocarcinoma，seven patients（15.9%）with extrahepatic cholangiocarcinoma，and11 patients（25.0%）with gallbladder cancer.There were three patients（6.8%）with locally advanced disease and 41 patients（93.2%）with metastatic disease.Baseline ECOG PS scores were 0 in six patients（13.6%），1 in 24 patients（54.5%），and 2 in 14 patients（31.8%）.The median ECOG PS score was 1（IQR，1–2）in the entire cohort.