《Table 1Top 10 autoimmune diseases ranked according to the total number of associated genes》
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《GAAD: A Gene and Autoimmiune Disease Association Database》
Note:A complete and up-to-date list of autoimmune diseases and the number of associated genes is available at http://gaad.medgenius.info/diseases/.
The number of genes associated with an AD ranges from1324(RA)to 2(vitiligo-associated multiple autoimmune disease),as shown in Table 1.Out of the associated genes in GAAD,more than half of the genes are associated with only one disease.Overall,the distribution of the number of diseases which a gene is associated with follows the power-law distribution(data from https://en.wikipedia.org/wiki/Power_law;accessed on July 20,2017)(Figure 2) .In total 33 genes are associated with more than 20 ADs(Table 2);not surprisingly,most genes are involved in immune response.
图表编号 | XD0021323200 严禁用于非法目的 |
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绘制时间 | 2018.08.01 |
作者 | Guanting Lu、Xiaowen Hao、Wei-Hua Chen、Shijie Mu |
绘制单位 | Department of Blood Transfusion, Tangdu Hospital, Fourth Military Medical University、MOE Key Laboratory of Molecular Biophysics, Hubei Key Laboratory of Bioinformatics and Molecular-imaging, Department of Bioinformatics and Systems Biology, College of Lif |
更多格式 | 高清、无水印(增值服务) |
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