《Table 1Top 10 autoimmune diseases ranked according to the total number of associated genes》

《Table 1Top 10 autoimmune diseases ranked according to the total number of associated genes》   提示:宽带有限、当前游客访问压缩模式
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《GAAD: A Gene and Autoimmiune Disease Association Database》


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Note:A complete and up-to-date list of autoimmune diseases and the number of associated genes is available at http://gaad.medgenius.info/diseases/.

The number of genes associated with an AD ranges from1324(RA)to 2(vitiligo-associated multiple autoimmune disease),as shown in Table 1.Out of the associated genes in GAAD,more than half of the genes are associated with only one disease.Overall,the distribution of the number of diseases which a gene is associated with follows the power-law distribution(data from https://en.wikipedia.org/wiki/Power_law;accessed on July 20,2017)(Figure 2) .In total 33 genes are associated with more than 20 ADs(Table 2);not surprisingly,most genes are involved in immune response.