《Table 2 Etiology of hypopituitarism and distribution of pituitary deficiencies in our patients n (%

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《Clinical characteristics of non-alcoholic fatty liver disease in Chinese adult hypopituitary patients》

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NAFLD:Non-alcoholic fatty liver disease.

The distribution of deficiency in anterior pituitary hormones is shown in Table 2，and all patients exhibited gonadotropin deficiency.The subjects who were on hormone replacement were evaluated clinically and biochemically at regular intervals，according to standard clinical practice，to ensure the physiological replacement of the deficient hormones.Although four（57.1%）cirrhotic patients were panhypopituitary，no significant differences were noted with regard to the distribution of deficiency in anterior pituitary hormones and to the proportion of patients who received physiological hormone replacement.No patient received GH therapy in the present study.No significant difference was noted in serum GH or insulin-like growth factor1（IGF1）.Serum thyroid hormone levels were similar in cirrhotic，NAFLD，and NAFLD（-）patients，as shown in Table 1.In addition，there was no difference in the proportion of patients with hypothalamic dysfunction in cirrhotic，NAFLD，and NAFLD（-）patients.